- Appearance: Physeptone tablets are typically white, uncoated, round, and biconvex.
- Markings: One side of the tablet is plain, while the other is scored with a marking indicating the dosage. For example, a 5mg tablet is marked “MART 5,” and a 10mg tablet is marked “MART 10”.
- Dosage: Tablets are available in different strengths, commonly 5mg and 10mg.
- Inactive ingredients: Excipients may include lactose, maize starch, gelatin, glycerol, and magnesium stearate.
Key characteristics and warnings
- Controlled substance: Methadone is a controlled substance with a high potential for misuse, abuse, and addiction.
- Respiratory depression: It can cause life-threatening or fatal breathing problems, especially during treatment initiation or after a dose increase.
- Overdose risk: Accidental ingestion by children can be fatal. In case of overdose, symptoms include severe drowsiness, difficulty breathing, pinpoint pupils, and loss of consciousness.
- Withdrawal symptoms: Sudden discontinuation can lead to unpleasant withdrawal symptoms, so the dose must be reduced gradually under a doctor’s supervision.
- Cardiac effects: Methadone may cause rare but serious heart rhythm problems, particularly at high doses.
- CNS depressants: Taking methadone with alcohol or other central nervous system (CNS) depressants can increase the risk of serious side effects like respiratory depression, profound sedation, and coma.
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